Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20466528 | 0.91 | TSHR (0.39) | TSHRTDP1 | |
| SCHEMBL20466522 | 0.82 | TDP1 (0.32) | TSHRTDP1 | |
| SCHEMBL14539386 | 0.81 | — | — | |
| SCHEMBL20466529 | 0.80 | TDP1 (0.31) | TSHRTDP1 | |
| SCHEMBL8986589 | 0.79 | TSHR (0.36) | TSHRHSD17B10TDP1 | |
| SCHEMBL13120944 | 0.79 | TSHR (0.43) | TSHRHSD17B10TDP1 | |
| Propylene Glycol SCHEMBL4452363 | 0.78 | TDP1 (0.56) | TSHRHSD17B10TDP1ALDH1A1 | |
| SCHEMBL887639 | 0.77 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL27602540 | 0.75 | TSHR (0.39) | TSHR | |
| SCHEMBL12563679 | 0.74 | TSHR (0.42) | TSHRHSD17B10TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0302341-B1 | ISOCYANATO-ACYL URETHANES, THEIR PREPARATION AND USE | BAYER AG (DE) | 1992-05-06 | — | — | EP | disclosed |
| US-4921996-A | Isocyanato-acylurethanes, a process for their preparation and their use | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-01 | — | — | US | disclosed |