Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626549 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL7823514 | 0.88 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9626317 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL5282151 | 0.86 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10584002 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9627124 | 0.81 | KDM4E (0.42) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10912342 | 0.81 | KDM4E (0.48) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10749384 | 0.79 | KDM4E (0.65) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL7821385 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Hydrochloric Acid SCHEMBL10502571 | 0.78 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198192-B1 | 7-AMINO-1-(SUBST.CYCLOPROPYL)-1,4 -DIHYDRO-4-OXO-QUINOLINE CARBOXYLIC ACIDS, METHOD FOR THEIR PREPARATION, AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1992-05-13 | — | — | EP | claimed |
| EP-0198192-B1 | 7-AMINO-1-(SUBST.CYCLOPROPYL)-1,4 -DIHYDRO-4-OXO-QUINOLINE CARBOXYLIC ACIDS, METHOD FOR THEIR PREPARATION, AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0198192-A1 | 7-Amino-1-(subst.cyclopropyl)-1,4 -dihydro-4-oxo-quinoline carboxylic acids, method for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-10-22 | — | — | EP | disclosed |