Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.43 |
| ▸ | HPGD | P15428 | 8/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 5/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627925 | 0.91 | KDM4E (0.42) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9626257 | 0.91 | ALDH1A1 (0.35) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9634951 | 0.88 | ALDH1A1 (0.51) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| Hydrochloric Acid SCHEMBL10501517 | 0.87 | ALDH1A1 (0.51) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL10862601 | 0.87 | KDM4E (0.54) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9626416 | 0.87 | KDM4E (0.54) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9627124 | 0.86 | KDM4E (0.42) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9627091 | 0.86 | KDM4E (0.42) | KDM4EHPGDHSD17B10ALDH1A1PMP22 | |
| SCHEMBL9236365 | 0.83 | TOP2A (0.38) | KDM4EALDH1A1TOP2ATOP2BPOLB | |
| SCHEMBL9047223 | 0.83 | TOP2A (0.38) | KDM4EALDH1A1TOP2ATOP2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0198192-B1 | 7-AMINO-1-(SUBST.CYCLOPROPYL)-1,4 -DIHYDRO-4-OXO-QUINOLINE CARBOXYLIC ACIDS, METHOD FOR THEIR PREPARATION, AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1992-05-13 | — | — | EP | claimed |
| EP-0198192-A1 | 7-Amino-1-(subst.cyclopropyl)-1,4 -dihydro-4-oxo-quinoline carboxylic acids, method for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-10-22 | — | — | EP | claimed |
| EP-0198192-B1 | 7-AMINO-1-(SUBST.CYCLOPROPYL)-1,4 -DIHYDRO-4-OXO-QUINOLINE CARBOXYLIC ACIDS, METHOD FOR THEIR PREPARATION, AND ANTIBACTERIAL AGENTS CONTAINING THEM | BAYER AG (DE) | 1992-05-13 | — | — | EP | disclosed |
| EP-0198192-A1 | 7-Amino-1-(subst.cyclopropyl)-1,4 -dihydro-4-oxo-quinoline carboxylic acids, method for their preparation, and antibacterial agents containing them | BAYER AG (DE) | 1986-10-22 | — | — | EP | disclosed |