Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | SNCA | P37840 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | CHAT | P28329 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27435036 | 0.90 | IDO1 (0.57) | TTRIDO1EDNRACYP1A2SNCA | |
| SCHEMBL5022978 | 0.84 | CNR1 (0.49) | TTRIDO1CYP1A2MEN1TP53 | |
| SCHEMBL5016478 | 0.84 | CNR1 (0.52) | TTRIDO1CYP1A2MEN1TP53 | |
| SCHEMBL15282372 | 0.84 | TTR (0.47) | TTREDNRACYP1A2SNCANSD2 | |
| SCHEMBL12221061 | 0.83 | TTR (0.46) | TTRIDO1CYP1A2SNCANSD2 | |
| SCHEMBL4726651 | 0.82 | TTR (0.42) | TTRIDO1FABP4CCNA2CDK2 | |
| SCHEMBL7757566 | 0.82 | TTR (0.56) | TTRIDO1EDNRACYP1A2SNCA | |
| SCHEMBL5024402 | 0.82 | CYP1A2 (0.43) | TTRIDO1EDNRACYP1A2SNCA | |
| SCHEMBL12041809 | 0.81 | TTR (0.45) | TTRIDO1EDNRACYP1A2SNCA | |
| SCHEMBL5016504 | 0.81 | CYP1A2 (0.42) | TTRIDO1EDNRACYP1A2SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205005-B1 | NEW BIOLOGICALLY ACTIVE FLUORESCENT CYCLIC NUCLEOTIDES | UNIVERSITA' DEGLI STUDI DI PARMA (IT) | 1992-05-13 | — | — | EP | claimed |