⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6623653 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL321514 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL16892583 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL5249458 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL321620 | 1.00 | — | — | |
| SCHEMBL5073216 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL788709 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL7458419 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL789051 | 1.00 | TRPA1 (0.41) | — | |
| SCHEMBL9474716 | 1.00 | TRPA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191482-B1 | 1,2,3-THIADIAZOL-5YL-UREA DERIVATIVES, USE THEREOF FOR REGULATING PLANT SENESCENCE AND PREPARATIONS CONTAINING THESE DERIVATIVES | USTAV EXPERIMENTALNI BOTANIKY AV CR V V I (CZ) | 2019-03-27 | — | — | EP | claimed |
| US-7319100-B2 | Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-01-15 | — | — | US | claimed |
| US-20070155740-A1 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-07-05 | — | — | US | claimed |
| US-7232583-B2 | Method for preparing isothiocyanate(s) from cruciferous plant material | KINJIRUSHI CO., LTD. (JP) | 2007-06-19 | — | — | US | claimed |
| US-7205306-B2 | Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2007-04-17 | — | — | US | claimed |
| EP-1392309-B1 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2007-01-17 | — | — | EP | claimed |
| EP-1392309-A4 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2006-01-18 | — | — | EP | claimed |
| EP-1392309-A1 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-03-03 | — | — | EP | claimed |
| EP-1379577-A1 | CONTROLLING SOLAR RADIATION IN SAFETY GLASS LAMINATES | Solutia Inc. (US) | 2004-01-14 | — | — | EP | claimed |
| US-20030171380-A1 | Substituted pyrazinones, pyridines and pyrimidines as corticotropin releasing factor ligands | BRISTOL-MYERS SQUIBB PHARMA COMPANY, (FORMERLY D/B/A DUPONT PHARMACEUTICALS COMPANY) | 2003-09-11 | — | — | US | claimed |
| WO-2002092090-A1 | SUBSTITUTED PYRAZINONES, PYRIDINES AND PYRIMIDINES AS CORTICOTROPIN RELEASING FACTOR LIGANDS | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-11-21 | — | — | WO | claimed |
| WO-2002077081-A1 | CONTROLLING SOLAR RADIATION IN SAFETY GLASS LAMINATES | SOLUTIA, INC. (US) | 2002-10-03 | — | — | WO | claimed |
| WO-2024105148-A1 | PLANTS WITH LOW SEED GLUCOSINOLATE CONTENT | UNIVERSITY OF COPENHAGEN (DK) | 2024-05-23 | — | — | WO | disclosed |
| US-20240115626-A1 | COMPOSITIONS AND METHODS TO INCREASE PRODUCTION OF ISOTHIOCYANATES | CHURCH & DWIGHT CO., INC. (US) | 2024-04-11 | — | — | US | disclosed |
| US-20240041733-A1 | DENTAL CARE COMPOSITION AND METHOD OF PROMOTING CALCIFICATION IN LIVING BODY TISSUE | KINJIRUSHI CO., LTD. (JP) | 2024-02-08 | — | — | US | disclosed |
| US-11801273-B2 | Compositions and methods to increase production of isothiocyanates | CHURCH & DWIGHT CO., INC. (US) | 2023-10-31 | — | — | US | disclosed |
| US-4354030-A | CONTROL OF AQUATIC VEGETATION | ELI LILLY AND COMPANY (US) | 1982-10-12 | — | — | US | disclosed |
| EP-0049539-A1 | Thiazole derivatives for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-04-14 | — | — | EP | disclosed |
| US-4284631-A | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| EP-0007633-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-06 | — | — | EP | disclosed |