Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10586688 | 1.00 | MAPT (0.58) | MAPTKDM4ELMNAHSD17B10CYP17A1 | |
| SCHEMBL7130331 | 0.89 | MAPT (0.60) | MAPTKDM4EPTPN1HSD17B2CA12 | |
| SCHEMBL7130328 | 0.89 | MAPT (0.60) | MAPTKDM4EPTPN1HSD17B2CA12 | |
| SCHEMBL9483132 | 0.89 | MAPT (0.60) | MAPTKDM4EPTPN1HSD17B2CA12 | |
| SCHEMBL25954197 | 0.89 | MAPT (0.52) | MAPTKDM4ELMNAHSD17B10PTPN1 | |
| SCHEMBL8956806 | 0.85 | MAPT (0.78) | MAPTKDM4ELMNAHSD17B10CA12 | |
| SCHEMBL9493542 | 0.85 | MAPT (0.78) | MAPTKDM4ELMNAHSD17B10CA12 | |
| SCHEMBL9493539 | 0.85 | MAPT (0.78) | MAPTKDM4ELMNAHSD17B10CA12 | |
| SCHEMBL6939271 | 0.84 | CA12 (0.59) | MAPTKDM4ELMNAHSD17B10CYP17A1 | |
| SCHEMBL8377627 | 0.82 | MAPT (0.69) | MAPTKDM4ELMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62181239-A | — | — | None | — | — | JP | disclosed |
| EP-0188222-B1 | NOVEL LIQUID CRISTALLINE COMPOUNDS HAVING SUBSTITUENTS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-4943386-A | FERROELECTRIC, GOOD RESPONSE AND MEMORY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1990-07-24 | — | — | US | disclosed |
| US-4828754-A | TILT-TYPE CHIRAL SMECTIC PHASE | DAINIPPON INK & CHEMICALS, INC. (JP) | 1989-05-09 | — | — | US | disclosed |
| JP-S62181239-A | LIQUID CRYSTAL COMPOUND | DAINIPPON INK & CHEM INC | 1987-08-08 | — | — | JP | disclosed |