Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 3/20 | 0.67 |
| ▸ | THRB | P10828 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.49 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315387 | 1.00 | THRA (0.67) | THRATHRBALDH1A1HPGDSMPD1 | |
| SCHEMBL9307742 | 1.00 | THRA (0.67) | THRATHRBALDH1A1HPGDSMPD1 | |
| SCHEMBL9626722 | 1.00 | THRA (0.67) | THRATHRBALDH1A1HPGDSMPD1 | |
| SCHEMBL11321553 | 1.00 | THRA (0.67) | THRATHRBALDH1A1HPGDSMPD1 | |
| SCHEMBL9578543 | 1.00 | THRA (0.67) | THRATHRBALDH1A1HPGDSMPD1 | |
| SCHEMBL11324626 | 0.98 | THRA (0.64) | THRATHRBALDH1A1HPGDSMPD1 | |
| SCHEMBL11322093 | 0.94 | THRA (0.59) | THRATHRBALDH1A1HPGDATM | |
| SCHEMBL9626608 | 0.90 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL11315317 | 0.90 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 | |
| SCHEMBL18682278 | 0.90 | THRA (0.68) | THRATHRBALDH1A1HPGDPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188222-B1 | NOVEL LIQUID CRISTALLINE COMPOUNDS HAVING SUBSTITUENTS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1992-04-29 | — | — | EP | disclosed |
| US-5098599-A | Aromatic esters with sulfide groups as liquid crystals | MITSUBISHI RAYON COMPANY LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-4943386-A | FERROELECTRIC, GOOD RESPONSE AND MEMORY | DAINIPPON INK & CHEMICALS, INC. (JP) | 1990-07-24 | — | — | US | disclosed |
| EP-0354355-A1 | Optically active compound and liquid crystal composition | MITSUBISHI RAYON CO., LTD. (JP) | 1990-02-14 | — | — | EP | disclosed |
| US-4828754-A | TILT-TYPE CHIRAL SMECTIC PHASE | DAINIPPON INK & CHEMICALS, INC. (JP) | 1989-05-09 | — | — | US | disclosed |
| EP-0188222-A2 | Novel liquid cristalline compounds having substituents | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-07-23 | — | — | EP | disclosed |