SCHEMBL96269

SCHEMBL96269

O=Cc1cc(F)cc(F)c1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.41
PTGS2 P35354 2/20 0.39
PTGS1 P23219 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
ALDH1A1 P00352 2/20 0.36
CYP2A6 P11509 1/20 0.36
NFE2L2 Q16236 1/20 0.36
BACE1 P56817 1/20 0.35
KDM4E B2RXH2 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL13735346 0.97 ERN1 (0.39) ERN1PTGS2PTGS1CES2CES1
SCHEMBL6854243 0.94 ERN1 (0.41) ERN1PTGS2PTGS1CES2CES1
SCHEMBL28963596 0.83 ALDH1A1 (0.41) ERN1PTGS2PTGS1ALDH1A1NFE2L2
SCHEMBL30166199 0.82 ERN1 (0.34) ERN1PTGS2PTGS1CES2CES1
SCHEMBL1949502 0.82 CA12 (0.55) ERN1PTGS2PTGS1CA12CA1
SCHEMBL3856495 0.82 ERN1 (0.34) ERN1ALDH1A1NFE2L2
SCHEMBL698784 0.82 CYP2A6 (0.42) ERN1PTGS2PTGS1ALDH1A1CYP2A6
SCHEMBL2186856 0.82 ERN1 (0.34) ERN1ALDH1A1NFE2L2
SCHEMBL30374708 0.82 ALDH1A1 (0.46) ERN1ALDH1A1NFE2L2
SCHEMBL613761 0.82 ALDH1A1 (0.46) ERN1ALDH1A1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2111 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119875052-A Ion polymer based on flexible main chain, anion exchange membrane and preparation method thereof 武汉轻工大学 2025-04-25 CN claimed
CN-119730553-A Solar cell and preparation method thereof 浙江爱旭太阳能科技有限公司 2025-03-28 CN claimed
CN-119424664-A Tumor microenvironment response pharmaceutical composition and preparation method and application thereof 北京大学 2025-02-14 CN claimed
CN-117143598-B High-entropy carbon quantum dot nanomaterial and preparation method and application thereof 中南大学 2024-11-08 CN claimed
CN-118496215-A Polyhydroxylated onium derivative with disubstituted benzene ring, preparation method and medical application thereof 中国药科大学 2024-08-16 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-117624148-A Polyhydroxy sulfonium salt derivative with disubstituted benzene ring, preparation method and medical application thereof 中国药科大学 2024-03-01 CN claimed
CN-117143598-A High-entropy carbon quantum dot nanomaterial and preparation method and application thereof 中南大学 2023-12-01 CN claimed
WO-2023214052-A1 METHOD FOR PRODUCING POLYETHERKETONEKETONE ARKEMA FRANCE (FR) 2023-11-09 WO claimed
US-6476268-B1 Preparation of N-benzylamines BASF AKTIENGESELLSCHAFT (DE) 2002-11-05 US claimed
WO-2002083123-A1 AURONES AS TELOMERASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2002-10-24 WO claimed
US-20020146633-A1 FLUORINATED AROMATIC ACETAL POLYMERS AND PHOTOSENSITIVE COMPOSITIONS CONTAINING SUCH POLYMERS KODAK POLYCHROME GRAPHICS L.L.C. 2002-10-10 US claimed
EP-1247799-A2 Process for the preparation of N-benzylamines BASF AKTIENGESELLSCHAFT (DE) 2002-10-09 EP claimed
US-6458503-B1 BLEND WITH DIAZO RESIN; LITHOGRAPHIC PRINTING PLATES; PHOTOPOLYMERIZATION AND CROSSLINKING KODAK POLYCHROME GRAPHICS LLC 2002-10-01 US claimed
WO-2002073315-A1 FLUORINATED AROMATIC ACETAL POLYMERS AND PHOTOSENSITIVE COMPOSITIONS CONTAINING SUCH POLYMERS KODAK POLYCHROME GRAPHICS COMPANY, LTD. (US) 2002-09-19 WO claimed
WO-2002057261-A2 DIAMINOTHIAZOLES AND THEIR USE AS INHIBITORS OF CYCLIN-DEPENDENT KINASE F. HOFFMANN-LA ROCHE AG (CH) 2002-07-25 WO claimed
US-6337368-B1 WATER INSOLUBLE CARRIERS WITH P-NITROBENZOIC ACID, AROMATIC AMINES, AMIDES, SULFONAMIDES AND HYDRAZIDES KANEKA CORPORATION (JP) 2002-01-08 US claimed
EP-1089980-A1 COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS Elan Pharmaceuticals, Inc. (US) 2001-04-11 EP claimed
WO-1999067221-A1 COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS ELAN PHARMACEUTICALS, INC. (US) 1999-12-29 WO claimed