Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16100685 | 0.79 | TRPA1 (0.35) | TRPA1 | |
| SCHEMBL11883270 | 0.76 | PTGS1 (0.37) | TDP1TRPA1 | |
| SCHEMBL20721697 | 0.74 | TRPA1 (0.45) | TDP1TRPA1MAPK1 | |
| SCHEMBL17072023 | 0.74 | TRPA1 (0.45) | TDP1TRPA1MAPK1 | |
| SCHEMBL19645 | 0.74 | TRPA1 (0.45) | TDP1TRPA1MAPK1 | |
| SCHEMBL5886044 | 0.73 | DPP4 (0.35) | — | |
| SCHEMBL10818718 | 0.72 | TRPA1 (0.43) | TDP1TRPA1 | |
| SCHEMBL9653938 | 0.71 | TDP1 (0.31) | TDP1 | |
| Alcohol SCHEMBL6578240 | 0.70 | TRPA1 (0.42) | TDP1TRPA1 | |
| Ethylene Glycol SCHEMBL2832859 | 0.70 | TRPA1 (0.42) | TDP1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278710-B1 | REACTION SYSTEM FOR PREPARATION OF DEFORMABLE POLYURETHANES | ICI AMERICAS INC. (US) | 1992-04-29 | — | — | EP | disclosed |
| EP-0255371-B1 | POLYUREAS PREPARED FROM A MIXTURE OF POLYAMINES AND A POLYISOCYANATE | ICI AMERICAS INC. (US) | 1992-03-25 | — | — | EP | disclosed |
| US-4798862-A | Polyureas prepared from a mixture of polyamines and polyisocyanate | ICI AMERICAS INC. (US) | 1989-01-17 | — | — | US | disclosed |
| EP-0278710-A2 | Reaction system for preparation of deformable polyurethanes | ICI AMERICAS INC. (US) | 1988-08-17 | — | — | EP | disclosed |
| EP-0255371-A1 | Polyureas prepared from a mixture of polyamines and a polyisocyanate | ICI AMERICAS INC. (US) | 1988-02-03 | — | — | EP | disclosed |
| US-4719247-A | Deformable polyurethane having improved cure time | ICI AMERICAS INC. (US) | 1988-01-12 | — | — | US | disclosed |