Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 14/20 | 0.68 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.47 |
| ▸ | PSMD11 | O00231 | 2/20 | 0.47 |
| ▸ | PSMD12 | O00232 | 2/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.47 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.47 |
| ▸ | PSMD3 | O43242 | 2/20 | 0.47 |
| ▸ | PSMC3 | P17980 | 2/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.47 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.47 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.47 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.47 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.47 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.47 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.47 |
| ▸ | PSMB6 | P28072 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | PSMC2 | P35998 | 2/20 | 0.47 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18614390 | 0.81 | PSMB8 (0.68) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL1781945 | 0.81 | PSMB8 (0.68) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL1781069 | 0.80 | PSMB8 (1.00) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL14755434 | 0.78 | PSMB8 (0.69) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL11391265 | 0.77 | PSMB8 (0.62) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL1425626 | 0.77 | PSMB8 (0.62) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL4103372 | 0.77 | PSMB8 (0.62) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL14755690 | 0.77 | PSMB8 (0.62) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL1505637 | 0.77 | PSMB8 (0.62) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL1780192 | 0.75 | PSMB8 (0.68) | PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274351-B1 | SUBSTITUTED 1,3,4-OXATHIAZOL-2-ONE STABILIZERS | CIBA-GEIGY AG (CH) | 1992-03-18 | — | — | EP | disclosed |
| EP-0274351-A1 | Substituted 1,3,4-oxathiazol-2-one stabilizers | CIBA-GEIGY AG (CH) | 1988-07-13 | — | — | EP | disclosed |
| US-4724246-A | Substituted 1,3,4-oxathiazol-2-one stabilizers | CIBA-GEIGY CORPORATION (US) | 1988-02-09 | — | — | US | disclosed |