Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 13/20 | 0.68 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.47 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.47 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.47 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.47 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.47 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.47 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.47 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.47 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.47 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.47 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.47 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.47 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | PSMC2 | P35998 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113266 | 0.81 | PSMB8 (0.59) | PSMB8NOTUMPSMB11PSMD11PSMD12 | |
| SCHEMBL459541 | 0.81 | PSMB8 (0.68) | PSMB8NOTUMPSMB11PSMD11PSMD12 | |
| SCHEMBL9627131 | 0.81 | PSMB8 (0.68) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL18614390 | 0.81 | PSMB8 (0.68) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL12614772 | 0.81 | PSMB8 (0.68) | PSMB8NOTUMPSMB11PSMD11PSMD12 | |
| SCHEMBL14755644 | 0.81 | PSMB8 (1.00) | PSMB8NOTUMPSMB11PSMD11PSMD12 | |
| SCHEMBL16363828 | 0.81 | PSMB8 (0.68) | PSMB8PSMB11PSMD11PSMD12PSMD14 | |
| SCHEMBL4103372 | 0.80 | PSMB8 (0.62) | PSMB8NOTUMPSMB11PSMD11PSMD12 | |
| SCHEMBL1425626 | 0.80 | PSMB8 (0.62) | PSMB8NOTUMPSMB11PSMD11PSMD12 | |
| SCHEMBL1505637 | 0.80 | PSMB8 (0.62) | PSMB8NOTUMPSMB11PSMD11PSMD12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118274-A1 | PROTEASOME INHIBITORS AND THEIR USE IN TREATING PATHOGEN INFECTION AND CANCER | CORNELL RESEARCH FOUNDATION, INC. (US) | 2011-05-19 | — | — | US | claimed |
| WO-2009026579-A1 | PROTEASOME INHIBITORS AND THEIR USE IN TREATING PATHOGEN INFECTION AND CANCER | CORNELL RESEARCH FOUNDATION, INC. (US) | 2009-02-26 | — | — | WO | claimed |
| US-9732051-B2 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2017-08-15 | — | — | US | disclosed |
| EP-2738163-B1 | AMIDINE COMPOUND OR SALT THEREOF | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-01-20 | — | — | EP | disclosed |
| EP-2738163-B1 | AMIDINE COMPOUND OR SALT THEREOF | TAISHO PHARMACEUTICAL CO LTD (JP) | 2016-01-20 | — | — | EP | disclosed |
| US-9078444-B2 | Isothiazoline derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2015-07-14 | — | — | US | disclosed |
| US-9045466-B2 | Amidine compound or salt thereof | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-06-02 | — | — | US | disclosed |
| US-9045466-B2 | Amidine compound or salt thereof | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-06-02 | — | — | US | disclosed |
| US-9045466-B2 | Amidine compound or salt thereof | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2015-06-02 | — | — | US | disclosed |
| US-20140378415-A1 | ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-12-25 | — | — | US | disclosed |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | BASF SE (DE) | 2014-12-11 | — | — | US | disclosed |
| US-20090131489-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | KUO GEE-HONG | 2009-05-21 | — | — | US | disclosed |
| US-7498351-B2 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-03 | — | — | US | disclosed |
| US-7498351-B2 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-03-03 | — | — | US | disclosed |
| WO-2009026579-A1 | PROTEASOME INHIBITORS AND THEIR USE IN TREATING PATHOGEN INFECTION AND CANCER | CORNELL RESEARCH FOUNDATION, INC. (US) | 2009-02-26 | — | — | WO | disclosed |
| EP-1684752-B1 | PHENOXYACETIC ACIDS DERIVATIVES USEFUL AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) DUAL AGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2007-05-16 | — | — | EP | disclosed |
| EP-1684752-A1 | PHENOXYACETIC ACIDS DERIVATIVES USEFUL AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) DUAL AGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2006-08-02 | — | — | EP | disclosed |
| US-7015329-B2 | 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N. V. (BE) | 2006-03-21 | — | — | US | disclosed |
| WO-2005041959-A1 | PHENOXYACETIC ACIDS DERIVATIVES USEFUL AS PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR) DUAL AGONISTS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-05-12 | — | — | WO | disclosed |
| US-20050096362-A1 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050096362-A1 | 4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs | PPARA, PPARG, PPARD | PSMB8 3816/4885NOTUM 1703/4885PSMB11 3423/4885 |
| US-20140378415-A1 | ISOTHIAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS | CBR3, C1S, HRH2 | PSMB8 3063/4885NOTUM 597/4885PSMB11 3325/4885 |
| US-20090131489-A1 | 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS | PPARA, PPARG, PPARD | PSMB8 3816/4885NOTUM 1703/4885PSMB11 3423/4885 |
| US-20110118274-A1 | PROTEASOME INHIBITORS AND THEIR USE IN TREATING PATHOGEN INFECTION AND CANCER | PSMB1, PSME1, PSMB2 | PSMB8 22/4885NOTUM 3210/4885PSMB11 7/4885 |
| US-20140364466-A1 | Isothiazoline compounds for combating invertebrate pests | PIR, ACHE, INMT | PSMB8 1110/4885NOTUM 297/4885PSMB11 899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.