Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150 | 0.82 | ALDH1A1 (0.42) | NAALAD2ALDH1A1ESR1CYP3A4ESR2 | |
| Hydrogen Peroxide SCHEMBL28311497 | 0.79 | NAALAD2 (0.41) | NAALAD2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL464934 | 0.79 | NAALAD2 (0.41) | NAALAD2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL25196391 | 0.78 | TSHR (0.43) | ALDH1A1ESR1MEN1KMT2ATSHR | |
| SCHEMBL11210589 | 0.78 | NAALAD2 (0.39) | NAALAD2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL9627142 | 0.77 | AKR1B1 (0.45) | ALDH1A1ESR1MEN1KMT2ATSHR | |
| SCHEMBL24407989 | 0.73 | EGLN1 (0.39) | NAALAD2TSHRFFAR3HDAC3HDAC1 | |
| SCHEMBL31094248 | 0.72 | TSHR (0.39) | TSHR | |
| SCHEMBL11852358 | 0.71 | TSHR (0.32) | TSHR | |
| SCHEMBL11403557 | 0.71 | NAALAD2 (0.41) | NAALAD2ALDH1A1ESR1CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273090-B1 | SOLUTION POLYMERIZATION OF ACRYLIC ACID DERIVED MONOMERS USING TERTIARY ALKYL( C5)-HYDROPEROXIDES | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1992-03-18 | — | — | EP | disclosed |
| US-4777230-A | HIGH SOLID COATINGS | PENNWALT CORPORATION (US) | 1988-10-11 | — | — | US | disclosed |
| EP-0273090-A1 | Solution polymerization of acrylic acid derived monomers using tertiary alkyl( C5)-hydroperoxides | ATOCHEM NORTH AMERICA, INC. (a Pennsylvania corp.) (US) | 1988-07-06 | — | — | EP | disclosed |