Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | CASP9 | P55211 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17688826 | 0.87 | HTT (0.65) | HTTKDM4EMAPTGAAHSD17B10 | |
| SCHEMBL17688827 | 0.87 | HTT (0.65) | HTTKDM4EMAPTGAAHSD17B10 | |
| SCHEMBL9659842 | 0.85 | CNR1 (0.42) | HTTKDM4EMAPTHSD17B10CNR1 | |
| SCHEMBL9628152 | 0.85 | CNR2 (0.42) | HTTMAPTTP53CNR1CNR2 | |
| SCHEMBL9713960 | 0.85 | CNR1 (0.44) | HTTKDM4EMAPTHSD17B10CNR1 | |
| SCHEMBL23271981 | 0.82 | HTT (0.45) | HTTKDM4EMAPTGAATP53 | |
| SCHEMBL9641928 | 0.81 | ELANE (0.41) | KDM4EMAPTTP53CNR1CNR2 | |
| SCHEMBL29370469 | 0.80 | HTT (0.63) | HTTKDM4EMAPTGAAHSD17B10 | |
| SCHEMBL515297 | 0.80 | HTT (0.63) | HTTKDM4EMAPTGAAHSD17B10 | |
| SCHEMBL17696404 | 0.79 | MAPT (0.69) | HTTKDM4EMAPTGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |