SCHEMBL17696404

SCHEMBL17696404

CCC(=O)Oc1c(C)cc(O)c2ccccc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.69
GAA P10253 7/20 0.69
KDM4E B2RXH2 5/20 0.69
HTT P42858 4/20 0.69
HSD17B10 Q99714 2/20 0.69
TP53 P04637 1/20 0.69
LMNA P02545 3/20 0.47
KMT2A Q03164 5/20 0.44
POLB P06746 4/20 0.44
MEN1 O00255 4/20 0.44
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
NPC1 O15118 1/20 0.44
RECQL P46063 1/20 0.44
MCL1 Q07820 3/20 0.41
PKM P14618 1/20 0.41
RAB9A P51151 1/20 0.41
GALK1 P51570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17688826 0.84 HTT (0.65) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL17688827 0.84 HTT (0.65) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL3597080 0.82 MAPT (1.00) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL30089732 0.82 KDM4E (0.45) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL20398470 0.82 KDM4E (0.45) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL9627505 0.82 EP300 (0.50) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL20398449 0.81 ELANE (0.50) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL29372061 0.81 ELANE (0.50) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL9628470 0.81 MAPT (0.46) MAPTGAAKDM4EHTTHSD17B10
SCHEMBL9627680 0.79 HTT (0.54) MAPTGAAKDM4EHTTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170260117-A1 Method of Making Vitamin K1 Sunny Pharmtech Inc. (TW) 2017-09-14 US disclosed
US-20170260117-A1 Method of Making Vitamin K1 Sunny Pharmtech Inc. (TW) 2017-09-14 US disclosed
WO-2016060670-A1 METHOD OF MAKING VITAMIN K1 Sunny Pharmtech Inc. (TW) 2016-04-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260117-A1 Method of Making Vitamin K1 PROC, VKORC1L1, VKORC1 MAPT 4650/4885GAA 2110/4885KDM4E 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.