Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.55 |
| ▸ | AR | P10275 | 5/20 | 0.47 |
| ▸ | PGR | P06401 | 4/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.42 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7020267 | 1.00 | CYP19A1 (0.55) | CYP19A1ARPGRNR3C2SLC22A1 | |
| SCHEMBL7027408 | 0.90 | CYP19A1 (0.55) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL9626851 | 0.87 | CYP19A1 (0.49) | CYP19A1ARPGRNR3C2SERPINA6 | |
| SCHEMBL7030182 | 0.87 | CYP19A1 (0.49) | CYP19A1ARPGRNR3C2SERPINA6 | |
| SCHEMBL13809835 | 0.86 | CYP19A1 (0.60) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL6905409 | 0.85 | AR (0.67) | CYP19A1ARPGRNR3C2SLC22A1 | |
| SCHEMBL4259619 | 0.85 | AR (0.67) | CYP19A1ARPGRNR3C2SLC22A1 | |
| SCHEMBL6853055 | 0.84 | CYP19A1 (0.51) | CYP19A1ARPGRNR3C2SERPINA6 | |
| SCHEMBL1656778 | 0.84 | CYP19A1 (0.62) | CYP19A1ARPGRNR3C2 | |
| SCHEMBL5973825 | 0.84 | CYP19A1 (0.62) | CYP19A1ARPGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145847-A | Antiestrogens | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-09-08 | — | — | US | disclosed |
| EP-0410554-A2 | 14,17-Alpha-ethano- and ethano-estratrienes, process for their production and their use in the production of pharmaceuticals | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-30 | — | — | EP | disclosed |