Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1337583 | 0.81 | MAPT (0.65) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL30320741 | 0.79 | MAPT (0.74) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL14351756 | 0.78 | MAPT (0.72) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL27259774 | 0.73 | MAPT (0.80) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL4750672 | 0.73 | MAPT (0.65) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL4750670 | 0.73 | MAPT (0.65) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL3105532 | 0.72 | HIF1A (0.45) | MAPTALDH1A1NPC1POLBRAB9A | |
| SCHEMBL6578393 | 0.70 | NPC1 (0.57) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL14352056 | 0.70 | NPC1 (0.57) | MAPTALDH1A1HRH3NPC1POLB | |
| SCHEMBL27924685 | 0.70 | MAPT (0.64) | MAPTALDH1A1HRH3NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345775-B1 | OXA- OR THIA-ZOLINE DERIVATIVE | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-4977171-A | INSECTICIDES | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1990-12-11 | — | — | US | disclosed |
| EP-0345775-A1 | Oxa- or thia-zoline derivative | YASHIMA CHEMICAL INDUSTRIAL CO., LTD. (JP) | 1989-12-13 | — | — | EP | disclosed |