Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 1/20 | 0.53 |
| ▸ | RXRG | P48443 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F7 | P08709 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 1/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21234325 | 0.87 | MAOB (0.67) | MAOBMAOAFFAR1RXRARXRB | |
| SCHEMBL9626742 | 0.86 | MAOB (0.56) | MAOBMAOAFFAR1RXRARXRB | |
| SCHEMBL9626523 | 0.84 | MAOB (0.54) | MAOBMAOAFFAR1RXRARXRB | |
| SCHEMBL9627112 | 0.83 | MAOB (0.58) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL9627186 | 0.83 | ACACB (0.64) | MAOBMAOAFFAR1RXRARXRB | |
| SCHEMBL9626469 | 0.83 | MAOB (0.66) | MAOBMAOAFFAR1RXRARXRB | |
| SCHEMBL9628042 | 0.82 | MAOB (0.61) | MAOBMAOARXRARXRBRXRG | |
| SCHEMBL10426966 | 0.82 | ACACB (0.58) | MAOBMAOAALOX5 | |
| SCHEMBL8935324 | 0.81 | F2 (0.64) | MAOBMAOAFFAR1RXRARXRB | |
| Hydrochloric Acid SCHEMBL7913851 | 0.81 | ACACB (0.56) | MAOBMAOAALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |