SCHEMBL9626469

SCHEMBL9626469

CC(N)c1ccc(OCc2cccc(Cl)c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOB P27338 6/20 0.66
MAOA P21397 2/20 0.58
FFAR1 O14842 1/20 0.56
RXRA P19793 1/20 0.56
RXRB P28702 1/20 0.56
RXRG P48443 1/20 0.56
DHFR P00374 1/20 0.54
ALOX5 P09917 1/20 0.53
PNMT P11086 1/20 0.53
MRGPRX4 Q96LA9 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21234325 0.89 MAOB (0.67) MAOBMAOAFFAR1RXRARXRB
SCHEMBL11212089 0.85 MAOB (0.70) MAOBMAOARXRARXRBRXRG
Isopropylamine SCHEMBL9628060 0.85 MAOB (0.65) MAOBMAOARXRARXRBRXRG
SCHEMBL9627722 0.83 MAOB (0.58) MAOBMAOAFFAR1RXRARXRB
SCHEMBL9626307 0.83 MAOB (0.58) MAOBMAOAFFAR1RXRARXRB
SCHEMBL16564407 0.82 MAOB (0.68) MAOBFFAR1
SCHEMBL8935327 0.82 MAOB (0.58) MAOBMAOAFFAR1RXRARXRB
SCHEMBL9626343 0.82 MAOB (0.67) MAOBMAOARXRARXRBRXRG
SCHEMBL7768214 0.81 MAOB (0.59) MAOBMAOAALOX5
SCHEMBL6376299 0.81 MAOB (0.59) MAOBMAOAALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0477184-A1 INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. FOURNIER INDUSTRIE ET SANTE (FR) 1992-04-01 EP disclosed
WO-1990011997-A2 INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. FOURNIER INNOVATION ET SYNERGIE (FR) 1990-10-18 WO disclosed