Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181480 | 1.00 | DRD2 (0.47) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL9627978 | 1.00 | DRD2 (0.47) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL9181463 | 1.00 | DRD2 (0.47) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL9312788 | 0.91 | DRD2 (0.47) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL8379888 | 0.91 | DRD2 (0.47) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL8379890 | 0.91 | DRD2 (0.47) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL9312793 | 0.91 | DRD2 (0.47) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL8518725 | 0.89 | DRD2 (0.44) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL8518723 | 0.89 | DRD2 (0.44) | DRD2L3MBTL1LSSSLC2A1SLC18A3 | |
| SCHEMBL8518719 | 0.89 | DRD2 (0.44) | DRD2L3MBTL1LSSSLC2A1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5174921-A | BICYCLOHEXYL DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 1992-12-29 | — | — | US | disclosed |