Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626522 | 0.82 | MAOB (0.60) | BCHEMAOBMAOA | |
| SCHEMBL9626451 | 0.82 | MAOB (0.61) | BCHEMAOBMAOAGRM5 | |
| SCHEMBL9627122 | 0.82 | MAOB (0.62) | BCHEMAOB | |
| SCHEMBL25309034 | 0.82 | BCHE (0.74) | BCHE | |
| SCHEMBL9628277 | 0.78 | MAOB (0.58) | FFAR1BCHEMAOBADAMTS4MMP13 | |
| SCHEMBL21340514 | 0.78 | FFAR1 (0.56) | FFAR1FFAR4MAOBADAMTS4MMP13 | |
| SCHEMBL14163905 | 0.77 | FFAR1 (0.63) | FFAR1FFAR4MAOBADAMTS4MMP13 | |
| SCHEMBL13232461 | 0.76 | GRM5 (0.62) | FFAR1FFAR4MAOBMAOACYP4F2 | |
| SCHEMBL8549374 | 0.76 | FFAR1 (0.60) | FFAR1FFAR4MAOBMAOACYP4F2 | |
| SCHEMBL9626408 | 0.76 | MAOB (0.57) | BCHEMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |