Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 8/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.53 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.53 |
| ▸ | VNN1 | O95497 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4029474 | 0.88 | NPC1 (0.57) | FFAR1FFAR4MAOBRAB9ANPC1 | |
| SCHEMBL13232461 | 0.87 | GRM5 (0.62) | FFAR1FFAR4MAOBMRGPRX4MAOA | |
| SCHEMBL14163905 | 0.86 | FFAR1 (0.63) | FFAR1FFAR4MAOBMRGPRX4MAOA | |
| SCHEMBL1248693 | 0.85 | MAOB (0.66) | FFAR1FFAR4MAOBMRGPRX4MAOA | |
| SCHEMBL22874523 | 0.84 | MAOB (0.62) | FFAR1FFAR4MAOBMRGPRX4RAB9A | |
| SCHEMBL18641315 | 0.84 | LTA4H (0.58) | FFAR1FFAR4MAOBSMN1; SMN2MAOA | |
| SCHEMBL2015368 | 0.84 | FFAR1 (0.60) | FFAR1FFAR4MAOBMRGPRX4MAOA | |
| SCHEMBL13439790 | 0.83 | FFAR1 (0.56) | FFAR1FFAR4MAOBMRGPRX4MAOA | |
| SCHEMBL21340514 | 0.83 | FFAR1 (0.56) | FFAR1FFAR4MAOBMRGPRX4MAOA | |
| SCHEMBL17217589 | 0.83 | MEN1 (0.46) | FFAR1FFAR4MAOBMRGPRX4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381750-B2 | Amino-phenoxymethyl-benzamide opioid receptor antagonists | ELI LILLY AND COMPANY (US) | 2008-06-03 | — | — | US | disclosed |
| US-20070287751-A1 | Opioid Receptor Antagonists | ELI LILLY AND COMPANY | 2007-12-13 | — | — | US | disclosed |
| EP-0832078-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1998-04-01 | — | — | EP | disclosed |
| WO-1996040659-A1 | N-HYDROXYUREAS AS ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287751-A1 | Opioid Receptor Antagonists | OPRK1, OPRM1, OPRD1 | FFAR1 56/4885FFAR4 167/4885MAOB 1104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.