Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547433 | 0.87 | ELANE (0.41) | CNR2 | |
| SCHEMBL8367595 | 0.78 | TNNI3 (0.41) | ESR1ESR2HTTTSHRSMN1; SMN2 | |
| SCHEMBL27759679 | 0.74 | MAPT (0.48) | ESR1ESR2HTTPTGS1PTGS2 | |
| SCHEMBL27957739 | 0.74 | GABRA1 (0.48) | ESR1ESR2KDM4ERCE1MAOB | |
| SCHEMBL8365842 | 0.74 | CNR1 (0.40) | ESR1ESR2HTTKDM4ETSHR | |
| SCHEMBL11216494 | 0.73 | ESR1 (0.51) | ESR1ESR2 | |
| SCHEMBL9177949 | 0.73 | KDM4E (0.38) | ESR1ESR2HTTKDM4ETSHR | |
| SCHEMBL8367616 | 0.73 | TYR (0.45) | ESR1HTTPTGS1PTGS2KDM4E | |
| SCHEMBL11249133 | 0.73 | ELANE (0.40) | CNR2POLB | |
| SCHEMBL28020176 | 0.73 | HDAC4 (0.46) | KDM4ETSHRSMN1; SMN2HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193197-B1 | IMPROVED STATIC RESISTANT X-RAY INTENSIFYING SCREENS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-29 | — | — | EP | disclosed |
| US-4225653-A | X-ray intensifying screen based on rare earth tantalate | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-30 | — | — | US | disclosed |