Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10458809 | 0.98 | L3MBTL1 (0.61) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| Hydrochloric Acid SCHEMBL10458788 | 0.98 | L3MBTL1 (0.61) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| Bromide SCHEMBL11311978 | 0.98 | L3MBTL1 (0.57) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| Hydrochloric Acid SCHEMBL8600409 | 0.98 | L3MBTL1 (0.61) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| Sulfuric Acid SCHEMBL10459948 | 0.91 | L3MBTL1 (0.50) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| SCHEMBL11357850 | 0.90 | L3MBTL1 (0.47) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| Bromide SCHEMBL11322608 | 0.88 | L3MBTL1 (0.46) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| SCHEMBL11720334 | 0.84 | L3MBTL1 (0.49) | L3MBTL1HRH1HRH4HRH2HRH3 | |
| SCHEMBL11221673 | 0.82 | L3MBTL1 (0.39) | L3MBTL1SLC47A1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL11035051 | 0.82 | L3MBTL1 (0.39) | L3MBTL1HRH2TDP1SLC47A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4916233-A | Method for production of 4-methyl-5-(2-aminoethyl)-thiomethyl)-imidazole | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1990-04-10 | — | — | US | claimed |
| EP-0339970-A2 | Method for production of 4-methyl-5-((2-aminoethyl)-thiomethyl)-imidazole | NIPPON SHOKUBAI CO., LTD. (JP) | 1989-11-02 | — | — | EP | claimed |
| US-4413129-A | FROM 4-METHYL-5-HYDROXYMETHYLIMIDAZOLE AND 2-AMINOETHANETHIOLSULFURIC ACID | SOGO PHARMACEUTICAL COMPANY, LTD. (JP) | 1983-11-01 | — | — | US | claimed |
| US-4347373-A | Derivatives of 4-methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole | TURCONI FRANCO | 1982-08-31 | — | — | US | claimed |
| EP-0036684-A1 | Derivatives of 4-methyl-5-(2-aminoethyl)-thiomethyl-imidazole having therapeutic activity | Turconi, Franco (IT) | 1981-09-30 | — | — | EP | claimed |
| EP-0004535-B1 | PROCESS FOR PREPARING 4-METHYL-5-((2-AMINOETHYL)-THIOMETHYL)-IMIDAZOLE-DIHYDRO CHLORIDE | BASF Aktiengesellschaft (DE) | 1981-04-29 | — | — | EP | claimed |
| EP-0025443-A1 | CYANO-UREAS, CYANO-THIOUREAS AND PREPARATION METHODS THEREOF | SOCIETE DE RECHERCHES ET DE SYNTHESES ORGANIQUES SA (CH) | 1981-03-25 | — | — | EP | claimed |
| EP-0006102-B1 | 1-HYDROXYMETHYLIMIDAZOLES, THEIR PREPARATION AND USE AS CHEMICAL INTERMEDIATES | BASF Aktiengesellschaft (DE) | 1981-02-11 | — | — | EP | claimed |
| WO-1980001914-A1 | CYANO-UREAS,CYANO-THIOUREAS AND PREPARATION METHODS THEREOF | RECH & SYNTHESES ORGANIQUES SA (CH) | 1980-09-18 | — | — | WO | claimed |
| JP-2076858-A | — | — | None | — | — | JP | disclosed |
| JP-2076858-A | — | — | None | — | — | JP | disclosed |
| JP-2049773-A | — | — | None | — | — | JP | disclosed |
| JP-59010582-A | — | — | None | — | — | JP | disclosed |
| JP-58188860-A | — | — | None | — | — | JP | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-4013769-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-03-22 | — | — | US | disclosed |
| US-4005205-A | PYRIMIDINE COMPOUNDS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-01-25 | — | — | US | disclosed |
| US-4000302-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-12-28 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |