Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629430 | 0.91 | NOTUM (0.37) | NOTUMGABRA1GABRB1GABRA2GABRB2 | |
| SCHEMBL3860896 | 0.84 | NOTUM (0.39) | NOTUMPRMT5WDR77 | |
| SCHEMBL9629417 | 0.83 | NOTUM (0.46) | NOTUMGABRA1GABRB1GABRA2GABRB2 | |
| SCHEMBL9629655 | 0.80 | NOTUM (0.43) | NOTUMGABRA1GABRB1GABRA2GABRB2 | |
| SCHEMBL9629513 | 0.80 | NOTUM (0.43) | NOTUMGABRA1GABRB1GABRA2GABRB2 | |
| SCHEMBL9628686 | 0.78 | NOTUM (0.42) | NOTUMGABRA1GABRB1GABRA2GABRB2 | |
| SCHEMBL3588518 | 0.75 | CNR2 (0.30) | PRMT5WDR77 | |
| SCHEMBL3588521 | 0.75 | PIK3C3 (0.38) | RAB9ANPC1 | |
| SCHEMBL13391811 | 0.75 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL4009734 | 0.73 | NOTUM (0.41) | NOTUMPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316783-B1 | PROCESS FOR THE PREPARATION OF HETERO-AROMATIC KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0316783-A1 | Process for the preparation of hetero-aromatic ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |