Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628686 | 0.98 | NOTUM (0.42) | NOTUMPSMB8PSMB9PSMB5IGF1R | |
| SCHEMBL9629513 | 0.96 | NOTUM (0.43) | NOTUMPSMB8PSMB9PSMB5IGF1R | |
| SCHEMBL9629417 | 0.92 | NOTUM (0.46) | NOTUMPSMB8PSMB9PSMB5IGF1R | |
| SCHEMBL9629430 | 0.84 | NOTUM (0.37) | NOTUMPSMB8PSMB9PSMB5IGF1R | |
| SCHEMBL11613001 | 0.80 | IGF1R (0.40) | PSMB8PSMB9PSMB5IGF1RCHRNB2 | |
| SCHEMBL20163165 | 0.80 | IGF1R (0.40) | PSMB8PSMB9PSMB5IGF1RCHRNB2 | |
| SCHEMBL15109557 | 0.80 | NOTUM (0.42) | NOTUMPSMB8PSMB9PSMB5IGF1R | |
| SCHEMBL9628642 | 0.80 | NOTUM (0.39) | NOTUMGABRA1GABRB1GABRA2GABRB2 | |
| SCHEMBL9629386 | 0.78 | NOTUM (0.38) | NOTUMGABRA1GABRB1GABRA2GABRB2 | |
| SCHEMBL24007232 | 0.78 | MAPK14 (0.36) | PSMB8PSMB9PSMB5IGF1RCHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316783-B1 | PROCESS FOR THE PREPARATION OF HETERO-AROMATIC KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0316783-A1 | Process for the preparation of hetero-aromatic ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |