SCHEMBL9628720

SCHEMBL9628720

C=CCN(CC=C)CON(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 8/20 0.42
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 1/20 0.38
OPRM1 P35372 3/20 0.37
OPRD1 P41143 3/20 0.37
OPRK1 P41145 3/20 0.37
ALDH1A1 P00352 3/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
TSHR P16473 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PYCR1 P32322 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2688603 0.79 BCHE (0.49) BCHEKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL516674 0.79 BCHE (0.49) BCHEKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL8423295 0.78 GAA (0.42) KMT2AMEN1SMN1; SMN2GAAALDH1A1
Hydrochloric Acid SCHEMBL10548138 0.77 BCHE (0.48) BCHEKMT2AKDM4EMEN1SMN1; SMN2
Hydrochloric Acid SCHEMBL3752186 0.77 BCHE (0.48) BCHEKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL24045856 0.75 GAA (0.40) BCHEKMT2AKDM4EMEN1GAA
SCHEMBL2364160 0.74 BCHE (0.49) BCHEKMT2AKDM4EMEN1SMN1; SMN2
SCHEMBL9629959 0.74 TSHR (0.42) KMT2ASMN1; SMN2ALDH1A1HTTTSHR
SCHEMBL12126078 0.73 CNR2 (0.50) BCHEKDM4EOPRM1ALDH1A1TSHR
Allylamine SCHEMBL10763380 0.73 BCHE (0.44) BCHEKMT2AKDM4EMEN1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0246189-B1 COMPOSITIONS STABILIZED BY AMINOXYALKYL AMINES CIBA-GEIGY AG (CH) 1992-03-11 EP disclosed
US-4757102-A For stabilizing plastic, polymer, or resin subject to oxidative, thermal and actinic degradation CIBA-GEIGY CORPORATION (US) 1988-07-12 US disclosed
EP-0246189-A2 Compositions stabilized by aminoxyalkyl amines CIBA-GEIGY AG (CH) 1987-11-19 EP disclosed