Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE known ✓ | P06276 | 4/20 | 0.48 |
| ▸ | OPRM1 known ✓ | P35372 | 3/20 | 0.46 |
| ▸ | OPRD1 known ✓ | P41143 | 3/20 | 0.46 |
| ▸ | OPRK1 known ✓ | P41145 | 3/20 | 0.46 |
| ▸ | GAA known ✓ | P10253 | 1/20 | 0.44 |
| ▸ | GRIN2D known ✓ | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B known ✓ | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 known ✓ | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A known ✓ | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B known ✓ | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C known ✓ | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A known ✓ | Q8TCU5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516674 | 0.98 | BCHE (0.49) | BCHEOPRM1OPRD1OPRK1GAA | |
| Hydrochloric Acid SCHEMBL10548138 | 0.96 | BCHE (0.48) | BCHEOPRM1OPRD1OPRK1GAA | |
| SCHEMBL2688603 | 0.93 | BCHE (0.49) | BCHEOPRM1OPRD1OPRK1GAA | |
| Hydrochloric Acid SCHEMBL2322266 | 0.88 | KDM4E (0.49) | BCHEOPRM1ALDH1A1TSHRCNR2 | |
| SCHEMBL2364160 | 0.88 | BCHE (0.49) | BCHEOPRM1OPRD1OPRK1GAA | |
| SCHEMBL3157529 | 0.87 | MAOB (0.48) | BCHEOPRM1OPRD1OPRK1GAA | |
| Allylamine SCHEMBL10763380 | 0.86 | BCHE (0.44) | BCHEOPRM1OPRD1OPRK1GAA | |
| Dimethylamine SCHEMBL11863280 | 0.86 | GAA (0.45) | BCHEOPRM1OPRD1OPRK1GAA | |
| SCHEMBL12126078 | 0.86 | CNR2 (0.50) | BCHEOPRM1ALDH1A1TSHRCNR2 | |
| Hydrochloric Acid SCHEMBL18553840 | 0.85 | HTT (0.50) | BCHEOPRM1OPRD1OPRK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4050080-A1 | WATERPROOF, OILPROOF AGENT COMPOSITION AND METHOD FOR PRODUCING SAME | AGC INC. (JP) | 2022-08-31 | — | — | EP | disclosed |
| US-20220204667-A1 | WATER- AND OIL-PROOFING COMPOSITION AND METHOD FOR ITS PRODUCTION | AGC Inc. (JP) | 2022-06-30 | — | — | US | disclosed |
| CN-114616375-A | Water and oil proofing composition and method for producing same | ＡＧＣ株式会社 | 2022-06-10 | — | — | CN | disclosed |
| WO-2021079774-A1 | WATERPROOF, OILPROOF AGENT COMPOSITION AND METHOD FOR PRODUCING SAME | ＡＧＣ株式会社 | 2021-04-29 | — | — | WO | disclosed |
| CN-104241712-A | Sodium battery containing ion liquid electrolyte and preparation method thereof | SHANGHAI INST CERAMICS | 2014-12-24 | — | — | CN | disclosed |
| EP-1899124-B1 | WOOD PRESERVATIVE COMPOSITION | UNION CARBIDE CHEM PLASTIC (US) | 2010-12-29 | — | — | EP | disclosed |
| US-7740692-B2 | Wood preservative composition | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY LLC | 2010-06-22 | — | — | US | disclosed |
| US-20090211487-A1 | Wood Preservative Composition | UNION CARBIDE CHEIMCALS & PLASTICS TECHNOLOGY LLC. CORPORATION TRUST CENTER (DE) | 2009-08-27 | — | — | US | disclosed |
| EP-1899124-A1 | WOOD PRESERVATIVE COMPOSITION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007005195-A1 | WOOD PRESERVATIVE COMPOSITION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2007-01-11 | — | — | WO | disclosed |
| US-4504995-A | Playing card cleaning apparatus | BELL, RALPH | 1985-03-19 | — | — | US | disclosed |