Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA2 | P00918 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | DRD3 | P35462 | 4/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2729745 | 0.91 | HRH3 (0.41) | HRH3CA12CA2CA9DRD2 | |
| SCHEMBL5358 | 0.91 | HRH3 (0.41) | HRH3CA12CA2CA9DRD2 | |
| SCHEMBL21224483 | 0.91 | HRH3 (0.41) | HRH3CA12CA2CA9DRD2 | |
| Methylene Chloride SCHEMBL6682460 | 0.88 | LMNA (0.41) | HRH3CA12CA2CA9DRD2 | |
| SCHEMBL756023 | 0.87 | HRH3 (0.39) | HRH3CA12CA2CA9DRD2 | |
| Iodide SCHEMBL1758226 | 0.87 | HRH3 (0.39) | HRH3CA12CA2CA9DRD2 | |
| Fluoride SCHEMBL64252 | 0.87 | HRH3 (0.39) | HRH3CA12CA2CA9DRD2 | |
| SCHEMBL10948053 | 0.87 | HRH3 (0.39) | HRH3CA12CA2CA9DRD2 | |
| SCHEMBL14270553 | 0.87 | HRH3 (0.39) | HRH3CA12CA2CA9DRD2 | |
| Hydrochloric Acid SCHEMBL210163 | 0.87 | HRH3 (0.39) | HRH3CA12CA2CA9DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101463119-A | Reactive isocyanate compositions | EVONIK DEGUSSA GMBH (DE) | 2009-06-24 | — | — | CN | claimed |
| CN-101463221-A | Dual cure formulations with components comprising uretdione groups | EVONIK DEGUSSA GMBH (DE) | 2009-06-24 | — | — | CN | claimed |
| CN-101139461-A | Low-temperature-curable polyurethane compositions containing uretdione groups and with quaternary ammonium halides | DEGUSSA (DE) | 2008-03-12 | — | — | CN | claimed |
| EP-0229714-B1 | POLYMERIZATION OF AROMATIC POLYAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-20 | — | — | EP | claimed |
| US-4737571-A | REACTING PHENYLENEDIAMINE WITH TEREPHTHALOYL CHLORIDE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-04-12 | — | — | US | claimed |
| EP-0229714-A2 | Polymerization of aromatic polyamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-22 | — | — | EP | claimed |
| CN-108863966-A | The method for preparing the trimer and/or oligomer of diisocyanate | 赢创德固赛有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-101497686-B | Dryblend process for preparing high-reactivity polyurethane compositions containing uretdione groups | EVONIK DEGUSSA GMBH (DE) | 2014-10-22 | — | — | CN | disclosed |
| CN-101497686-A | Dryblend process for preparing high-reactivity polyurethane compositions containing uretdione groups | EVONIK DEGUSSA GMBH (DE) | 2009-08-05 | — | — | CN | disclosed |
| CN-101463119-A | Reactive isocyanate compositions | EVONIK DEGUSSA GMBH (DE) | 2009-06-24 | — | — | CN | disclosed |
| CN-101463221-A | Dual cure formulations with components comprising uretdione groups | EVONIK DEGUSSA GMBH (DE) | 2009-06-24 | — | — | CN | disclosed |
| CN-101139461-A | Low-temperature-curable polyurethane compositions containing uretdione groups and with quaternary ammonium halides | DEGUSSA (DE) | 2008-03-12 | — | — | CN | disclosed |
| CN-1635992-A | Solventless synthesis of hydrophilic phenol ester derivatives | PROCTER & GAMBLE (US) | 2005-07-06 | — | — | CN | disclosed |
| EP-0229714-B1 | POLYMERIZATION OF AROMATIC POLYAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |