Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10353021 | 0.96 | NOTUM (0.54) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL10636595 | 0.90 | NOTUM (0.65) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL9628923 | 0.81 | NOTUM (0.79) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL9629591 | 0.77 | DRD4 (0.57) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL1909835 | 0.76 | CA12 (0.45) | NOTUMHPGDSMN1; SMN2HDAC1HDAC6 | |
| SCHEMBL10352868 | 0.76 | NOTUM (0.82) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL9629606 | 0.75 | GSK3B (0.53) | NOTUMKDM4ELMNASMN1; SMN2HDAC1 | |
| SCHEMBL7413168 | 0.74 | DRD4 (0.59) | NOTUMKDM4EDRD4L3MBTL1LMNA | |
| SCHEMBL1911604 | 0.73 | SMN1; SMN2 (0.68) | NOTUMHPGDSMN1; SMN2POLBMAPT | |
| SCHEMBL29876158 | 0.72 | DRD4 (0.61) | NOTUMKDM4EDRD4L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |