SCHEMBL9628833

SCHEMBL9628833

COc1ccc(Cl)cc1.COc1cccc(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 2/20 0.58
LMNA P02545 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
HPGD P15428 1/20 0.50
PGR P06401 1/20 0.49
ACHE P22303 1/20 0.48
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
EGFR P00533 1/20 0.47
ERBB3 P21860 1/20 0.47
ENPP2 Q13822 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP3A4 P08684 1/20 0.47
TP53 P04637 1/20 0.46
MAPT P10636 1/20 0.46
NFE2L2 Q16236 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6203985 0.91
SCHEMBL29635640 0.91
SCHEMBL70822 0.91
Water SCHEMBL27909580 0.89 ACHE (0.54) RELAPGRACHENPC1RAB9A
SCHEMBL1794813 0.89 ACHE (0.54) RELAPGRACHENPC1RAB9A
Naphthalene SCHEMBL10873174 0.83 CYP2A6 (0.59) RELAACHENPC1RAB9AEGFR
SCHEMBL4621505 0.83 NPC1 (0.51) RELALMNAHPGDACHENPC1
SCHEMBL2226770 0.82
SCHEMBL154527 0.82
SCHEMBL3746980 0.82 SMN1; SMN2 (0.67) LMNANPSR1PGRRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166350-A Process for the manufacture of fluoran compounds CIBA-GEIGY CORPORATION (US) 1992-11-24 US disclosed