Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629700 | 0.78 | BRD4 (0.57) | ALDH1A1SMN1; SMN2GAAHTTMEN1 | |
| SCHEMBL9628917 | 0.71 | MAOA (0.42) | MAOAMAOBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL705947 | 0.70 | MAOB (0.79) | MAOAMAOBALDH1A1HTTNOX1 | |
| SCHEMBL9628766 | 0.69 | MAOA (0.55) | MAOAMAOBALDH1A1HTTNOX1 | |
| SCHEMBL9629535 | 0.68 | CRBN (0.35) | ALDH1A1SMN1; SMN2BRD4CREBBP | |
| SCHEMBL8853694 | 0.68 | MAOA (0.57) | MAOAMAOBALDH1A1HTTNOX1 | |
| SCHEMBL9636627 | 0.68 | RYR2 (0.47) | MAOAMAOBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL1038757 | 0.66 | SMN1; SMN2 (0.52) | MAOAMAOBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14188944 | 0.65 | SMN1; SMN2 (0.51) | MAOAMAOBALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14188939 | 0.65 | SMN1; SMN2 (0.51) | MAOAMAOBALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340581-B1 | PROCESS FOR THE CHLORINATION IN THE NUCLEUS OF AROMATIC HYDROCARBONS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| US-4925994-A | Process for the ring chlorination of aromatic hydrocarbons | BAYER AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| EP-0340581-A2 | Process for the chlorination in the nucleus of aromatic hydrocarbons | BAYER AG (DE) | 1989-11-08 | — | — | EP | disclosed |