Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10351106 | 0.74 | APEX1 (0.30) | APEX1BLM | |
| SCHEMBL10351032 | 0.73 | APEX1 (0.32) | APEX1BLM | |
| SCHEMBL9628933 | 0.72 | TSHR (0.45) | DDB1CRBN | |
| SCHEMBL9821185 | 0.70 | TSHR (0.39) | DDB1CRBN | |
| SCHEMBL11513794 | 0.67 | CHRM2 (0.36) | DDB1CRBN | |
| Oxiracetam SCHEMBL15789330 | 0.65 | APEX1 (1.00) | APEX1BLM | |
| Oxiracetam SCHEMBL526050 | 0.65 | APEX1 (1.00) | APEX1BLM | |
| Oxiracetam SCHEMBL2596758 | 0.65 | APEX1 (1.00) | APEX1BLM | |
| Oxiracetam SCHEMBL15789157 | 0.64 | APEX1 (0.96) | APEX1BLM | |
| Oxiracetam SCHEMBL28956553 | 0.64 | APEX1 (0.96) | APEX1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207681-B1 | PYRROLIDONE DERIVATIVES | ISF SOCIETA PER AZIONI (IT) | 1992-03-18 | — | — | EP | claimed |
| US-4824861-A | Pyrrolidone derivatives and memory enhancement use thereof | ISF SOCIETA PER AZIONI (IT) | 1989-04-25 | — | — | US | claimed |
| EP-0207681-A2 | Pyrrolidone derivatives | ISF SOCIETA PER AZIONI (IT) | 1987-01-07 | — | — | EP | claimed |
| EP-0207681-B1 | PYRROLIDONE DERIVATIVES | ISF SOCIETA PER AZIONI (IT) | 1992-03-18 | — | — | EP | disclosed |
| US-4868313-A | LEARNING ENHANCEMENT | I.S.F. SOCIETA PER AZIONI (IT) | 1989-09-19 | — | — | US | disclosed |
| US-4868313-A | LEARNING ENHANCEMENT | I.S.F. SOCIETA PER AZIONI (IT) | 1989-09-19 | — | — | US | disclosed |
| US-4824861-A | Pyrrolidone derivatives and memory enhancement use thereof | ISF SOCIETA PER AZIONI (IT) | 1989-04-25 | — | — | US | disclosed |
| US-4824861-A | Pyrrolidone derivatives and memory enhancement use thereof | ISF SOCIETA PER AZIONI (IT) | 1989-04-25 | — | — | US | disclosed |
| EP-0207681-A2 | Pyrrolidone derivatives | ISF SOCIETA PER AZIONI (IT) | 1987-01-07 | — | — | EP | disclosed |