Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628933 | 0.94 | TSHR (0.45) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL11242674 | 0.77 | LMNA (0.40) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL11512589 | 0.76 | KMT2A (0.39) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL9587421 | 0.74 | LMNA (0.38) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL11513892 | 0.74 | LMNA (0.36) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL11245719 | 0.73 | LMNA (0.37) | TSHRLMNACA12CA1CA2 | |
| SCHEMBL11512062 | 0.72 | ALDH1A1 (0.38) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9628966 | 0.70 | APEX1 (0.47) | DDB1CRBN | |
| SCHEMBL11513318 | 0.70 | ALDH1A1 (0.40) | CYP1A2KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL11512525 | 0.69 | HTT (0.56) | TSHRLMNAKMT2AL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021568-A | Lactam-1-acetic acid carbalkoxymethyl esters and method for preparing same | SHIPOV ALEXANDR G (SU) | 1991-06-04 | — | — | US | disclosed |
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |