Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | MAPT | P10636 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | PDE5A | O76074 | 7/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.74 |
| ▸ | GLA | P06280 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.72 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 3/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.71 |
| ▸ | ATM | Q13315 | 2/20 | 0.71 |
| ▸ | CDC42 | P60953 | 1/20 | 0.71 |
| ▸ | EGFR | P00533 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126048 | 0.94 | PDE5A (0.83) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL11122272 | 0.94 | PDE5A (0.83) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL15301136 | 0.94 | KDM4E (0.88) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL15301042 | 0.91 | MEN1 (0.83) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8171663 | 0.91 | MEN1 (0.83) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL15301347 | 0.89 | MEN1 (0.82) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL10362296 | 0.89 | EGFR (0.81) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL16740584 | 0.88 | KDM4E (0.78) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL25667063 | 0.88 | KDM4E (0.82) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL12493661 | 0.87 | PDE5A (1.00) | MEN1KMT2AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095029-A | FUNGICIDAL 1,3,5-TRIARYL-2-PYRAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| EP-0409026-A1 | Fungicidal agent based on 1,3,5-triaryl-2-pyrazolin derivatives new 1,3,5-triaryl-2-pyrazolins and process for their preparation | BAYER AG (DE) | 1991-01-23 | — | — | EP | disclosed |