Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9629146 | 0.88 | MAPT (0.49) | HPGDALDH1A1KDM4EGAAPDE4B | |
| SCHEMBL9629742 | 0.87 | CYP2C19 (0.47) | HPGDALDH1A1PDE4BPDE4DPDE4A | |
| SCHEMBL10377092 | 0.87 | EPHB4 (0.48) | POLBPDE4BPDE4DL3MBTL1CYP1A2 | |
| SCHEMBL10422443 | 0.86 | PDE4B (0.42) | HPGDPDE4BPDE4DPDE4APDE4C | |
| SCHEMBL9630002 | 0.86 | FEN1 (0.50) | ALDH1A1KDM4EPDE4BPDE4DPDE4A | |
| SCHEMBL10659551 | 0.85 | EPHB4 (0.38) | PDE4BPDE4DPDE4APDE4CFEN1 | |
| SCHEMBL10661052 | 0.84 | PDE4A (0.36) | HPGDALDH1A1PDE4BPDE4DPDE4A | |
| SCHEMBL9629666 | 0.83 | MAPT (0.40) | HPGDALDH1A1KDM4EPDE4BPDE4D | |
| SCHEMBL9629733 | 0.83 | MET (0.39) | ALDH1A1PDE4BPDE4DPDE4APDE4C | |
| SCHEMBL9630934 | 0.82 | KAT2B (0.45) | HPGDALDH1A1KDM4EGAAPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0338010-B1 | PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HYPERPROLIFERATE SKIN DISEASE | SCHERING CORPORATION (US) | 1992-02-05 | — | — | EP | claimed |