SCHEMBL9629220

SCHEMBL9629220

O=[N+]([O-])c1nnc([N+](=O)[O-])c([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
TSHR P16473 3/20 0.35
TDP1 Q9NUW8 1/20 0.35
PKM P14618 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.30
S100A4 P26447 1/20 0.30
GPR35 Q9HC97 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2056834 0.82 TSHR (0.32) ALDH1A1TSHRTDP1PKMKDM4E
Water SCHEMBL27388923 0.80 TSHR (0.31) ALDH1A1TSHRTDP1GPR35
SCHEMBL1194020 0.71 TSHR (0.45) ALDH1A1TSHRTDP1PKMCYP3A4
SCHEMBL9629226 0.69 KDM4E (0.36) ALDH1A1TSHRKDM4EGAA
SCHEMBL30398243 0.68 MAPT (0.37) ALDH1A1TSHRTDP1KDM4EGAA
SCHEMBL27818193 0.67 PKM (0.36) ALDH1A1PKMCYP3A4S100A4
Ethylene SCHEMBL27824111 0.65 TSHR (0.41) ALDH1A1TSHRTDP1PKMCYP3A4
SCHEMBL35451 0.65 KMT2A (0.34) ALDH1A1KDM4EGAA
SCHEMBL3722614 0.62 KDM4E (0.41) ALDH1A1KDM4EGAA
SCHEMBL11028700 0.62 MAPT (0.36) ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802394-B1 PROMOTED CALCIUM-ALUMINATE SUPPORTED CATALYSTS FOR SYNTHESIS GAS GENERATION CLARIANT CORP (US) 2020-10-21 EP claimed
US-5106913-A Improving dynamic properties of vulcanized rubber with a dinitrodiamine derivative; scorch resistant, resilient SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-04-21 US disclosed
EP-0253365-B1 RUBBER COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-11-27 EP disclosed
EP-0253365-A2 Rubber composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1988-01-20 EP disclosed