Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 6/20 | 0.40 |
| ▸ | CA9 | Q16790 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecylamine SCHEMBL28533028 | 1.00 | TP53 (0.47) | TP53DNM1MEN1KMT2AALDH1A1 | |
| Dodecylamine SCHEMBL1411815 | 0.94 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Decylamine SCHEMBL6898774 | 0.94 | DNM1 (0.52) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Dodecylamine SCHEMBL27941330 | 0.93 | DNM1 (0.50) | DNM1MEN1KMT2AALDH1A1TSHR | |
| Octane SCHEMBL28616568 | 0.84 | CA1 (0.46) | TP53TSHRCA1CA2CA9 | |
| Dodecane SCHEMBL28621410 | 0.84 | CA1 (0.46) | TP53TSHRCA1CA2CA9 | |
| Undecane SCHEMBL28633727 | 0.84 | CA1 (0.46) | TP53TSHRCA1CA2CA9 | |
| N,N-Dimethylethanaminium SCHEMBL27996738 | 0.84 | DNM1 (0.40) | TP53DNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL23004114 | 0.83 | TP53 (0.50) | TP53GNAI3GNAO1GNAI1CA1 | |
| SCHEMBL23004537 | 0.83 | TP53 (0.50) | TP53GNAI3GNAO1GNAI1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238994-B1 | PROCESS FOR PREPARING HIGH PURITY DERMATAN-SULPHATE, AND PHARMACEUTICAL COMPOSITIONS WICH CONTAIN IT | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1991-07-17 | — | — | EP | claimed |
| US-4870166-A | EXTRACTION FROM ANIMAL ORGANS | MEDIOLANUM FARMACEUTICI SRL (IT) | 1989-09-26 | — | — | US | claimed |
| EP-0238994-A2 | Process for preparing high purity dermatan-sulphate, and pharmaceutical compositions wich contain it | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1987-09-30 | — | — | EP | claimed |
| US-5116963-A | Anticoagulants | MEDIOLANUM FARMACEUTICI SRL (IT) | 1992-05-26 | — | — | US | disclosed |
| EP-0238994-B1 | PROCESS FOR PREPARING HIGH PURITY DERMATAN-SULPHATE, AND PHARMACEUTICAL COMPOSITIONS WICH CONTAIN IT | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1991-07-17 | — | — | EP | disclosed |
| US-4870166-A | EXTRACTION FROM ANIMAL ORGANS | MEDIOLANUM FARMACEUTICI SRL (IT) | 1989-09-26 | — | — | US | disclosed |
| EP-0238994-A2 | Process for preparing high purity dermatan-sulphate, and pharmaceutical compositions wich contain it | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1987-09-30 | — | — | EP | disclosed |