Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 3/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CASP9 | P55211 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628492 | 0.93 | MEN1 (0.49) | CYP2C9CNR1CNR2SLC2A1TLR8 | |
| SCHEMBL9629330 | 0.93 | MEN1 (0.49) | CYP2C9CNR1CNR2SLC2A1TLR8 | |
| SCHEMBL17912856 | 0.92 | SLC2A1 (0.52) | CYP2C9CYP1A2CYP2C19CNR1CNR2 | |
| SCHEMBL9628336 | 0.91 | CNR1 (0.46) | CYP2C9CNR1CNR2SLC2A1KCNH2 | |
| SCHEMBL9627447 | 0.89 | MEN1 (0.46) | CYP2C9CNR1CNR2SLC2A1L3MBTL1 | |
| SCHEMBL29700322 | 0.88 | KCNH2 (0.47) | CYP2C9CYP1A2CYP2C19CNR1CNR2 | |
| SCHEMBL9654902 | 0.88 | KCNH2 (0.47) | CYP2C9CYP1A2CYP2C19CNR1CNR2 | |
| SCHEMBL17912836 | 0.88 | LTA4H (0.53) | CYP2C9CYP1A2CYP2C19CNR1CNR2 | |
| SCHEMBL17912867 | 0.87 | HTT (0.49) | CYP2C9CYP1A2CYP2C19CNR1CNR2 | |
| SCHEMBL9627912 | 0.87 | HTT (0.48) | CYP2C9CNR1CNR2SLC2A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |