Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2309314 | 0.82 | ALDH1A1 (0.54) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL30178197 | 0.79 | ALDH1A1 (0.50) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL10732474 | 0.79 | ALDH1A1 (0.50) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL23888282 | 0.79 | POLB (0.59) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL15834222 | 0.77 | TDP1 (0.72) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL14420116 | 0.77 | TDP1 (0.49) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL10912275 | 0.77 | TDP1 (0.72) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL28034520 | 0.77 | TDP1 (0.51) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL11855341 | 0.76 | POLB (0.52) | TDP1L3MBTL1POLBKDM4ECTDSP1 | |
| SCHEMBL12190644 | 0.76 | SMN1; SMN2 (0.54) | TDP1L3MBTL1POLBKDM4ECTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0485157-A2 | Esters and amides of substituted pyrrole acetic acids | FGN, INC. (US) | 1992-05-13 | — | — | EP | disclosed |