Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 14/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 6/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076529 | 0.80 | KDM4E (0.42) | SIRT1MCL1KDM4EPOLBL3MBTL1 | |
| SCHEMBL1792301 | 0.76 | MCL1 (0.53) | SIRT1SIRT2MCL1EPHX1CYP1A2 | |
| SCHEMBL3968327 | 0.76 | MCL1 (0.53) | SIRT1SIRT2MCL1EPHX1CYP1A2 | |
| SCHEMBL7499527 | 0.76 | SIRT1 (0.38) | SIRT1SIRT2MCL1EPHX1KDM4E | |
| SCHEMBL9931272 | 0.76 | MCL1 (0.53) | SIRT1SIRT2MCL1EPHX1CYP1A2 | |
| SCHEMBL17301598 | 0.74 | MCL1 (0.52) | SIRT1SIRT2MCL1EPHX1CYP1A2 | |
| SCHEMBL10284785 | 0.74 | SIRT1 (0.37) | SIRT1SIRT2MCL1EPHX1KDM4E | |
| SCHEMBL21477523 | 0.74 | MCL1 (0.52) | SIRT1SIRT2MCL1EPHX1CYP1A2 | |
| SCHEMBL27904698 | 0.74 | MCL1 (0.52) | SIRT1SIRT2MCL1EPHX1CYP1A2 | |
| SCHEMBL8741700 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147719-A | Coatings, impact strength | PHILLIPS PETROLEUM COMPANY (US) | 1992-09-15 | — | — | US | disclosed |