Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630120 | 1.00 | CYP1A2 (0.33) | CYP1A2TRPV4MAOAMAOBCHRM2 | |
| SCHEMBL9630105 | 0.96 | TRPV4 (0.32) | TRPV4MAOAMAOBCHRM2CHRM1 | |
| SCHEMBL9630110 | 0.96 | TRPV4 (0.32) | TRPV4MAOAMAOBCHRM2CHRM1 | |
| SCHEMBL9632193 | 0.95 | CYP3A4 (0.32) | TRPV4 | |
| SCHEMBL9631700 | 0.95 | CYP3A4 (0.32) | TRPV4 | |
| SCHEMBL9632195 | 0.95 | CYP3A4 (0.32) | TRPV4 | |
| SCHEMBL9631649 | 0.95 | CYP3A4 (0.32) | TRPV4 | |
| SCHEMBL9631696 | 0.95 | CYP3A4 (0.32) | TRPV4 | |
| SCHEMBL9631653 | 0.95 | CYP3A4 (0.32) | TRPV4 | |
| SCHEMBL9630828 | 0.95 | CYP3A4 (0.32) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316715-B1 | CYCLOHEXANE DERIVATIVES | Chisso Corporation (JP) | 1992-06-03 | — | — | EP | disclosed |
| US-4853152-A | Cyclohexane derivative | CHISSO CORPORATION (JP) | 1989-08-01 | — | — | US | disclosed |
| EP-0316715-A2 | Cyclohexane derivatives | Chisso Corporation (JP) | 1989-05-24 | — | — | EP | disclosed |