Dimethylamine

Dimethylamine

SCHEMBL963016

CCCCCCC(c1ccccc1C)c1ccccc1C.CNC

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 1/20 0.41
CYSLTR1 Q9Y271 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
CYP19A1 P11511 2/20 0.41
CSNK1E P49674 1/20 0.40
CNR2 P34972 1/20 0.39
P2RX7 Q99572 1/20 0.38
PPARG P37231 1/20 0.37
ESR1 P03372 1/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
ALDH1A1 P00352 1/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diethylamine SCHEMBL2382514 0.90 CYSLTR2 (0.40) CYSLTR2CYSLTR1MEN1KMT2ANPSR1
Dimethylamine SCHEMBL10776458 0.87 CYP19A1 (0.46) KMT2ANPSR1CYP19A1ESR1HTR2A
SCHEMBL5271975 0.86 CYP19A1 (0.52) CYSLTR2CYSLTR1MEN1KMT2ANPSR1
SCHEMBL10779699 0.86 EPHX2 (0.42) MEN1KMT2ACSNK1ECNR2
SCHEMBL10776396 0.84 SCN8A (0.42) MEN1KMT2ACYP19A1CSNK1ECNR2
SCHEMBL7648740 0.84 CYSLTR2 (0.48) CYSLTR2CYSLTR1MEN1KMT2ANPSR1
SCHEMBL6547454 0.84 CYSLTR2 (0.48) CYSLTR2CYSLTR1MEN1KMT2ANPSR1
SCHEMBL11625320 0.81 NR1I2 (0.43) CYSLTR2CYSLTR1MEN1KMT2ANPSR1
SCHEMBL20520275 0.79 ALDH1A1 (0.43) CYSLTR2CYSLTR1MEN1KMT2ANPSR1
SCHEMBL20520217 0.79 ALDH1A1 (0.43) CYSLTR2CYSLTR1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7873298-B2 Cleaning device, process cartridge, and image forming apparatus RICOH COMPANY, LTD. (JP) 2011-01-18 US disclosed
US-7817954-B2 Cleaning unit, image carrier unit including same, and image forming apparatus including same RICOH COMPANY LIMITED (JP) 2010-10-19 US disclosed
US-20090092428-A1 CLEANING UNIT, IMAGE CARRIER UNIT INCLUDING SAME, AND IMAGE FORMING APPARATUS INCLUDING SAME RICOH COMPANY LIMITED (JP) 2009-04-09 US disclosed
US-20080170878-A1 Cleaning device, process cartridge, and image forming apparatus RICOH COMPANY, LTD. (JP) 2008-07-17 US disclosed
US-5589926-A Color image forming apparatus for forming a color image by transferring color toner to transfer member CANON KABUSHIKI KAISHA (JP) 1996-12-31 US disclosed