Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.31 |
| ▸ | FEN1 | P39748 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631259 | 0.91 | HTR2C (0.33) | FFAR1IDO1ACACBALOX5APFEN1 | |
| SCHEMBL9405701 | 0.91 | KDM1A (0.36) | TRPV3KDM1AALOX5APFEN1GRIN1 | |
| SCHEMBL12716045 | 0.91 | KDM1A (0.36) | TRPV3KDM1AALOX5APFEN1GRIN1 | |
| SCHEMBL9405698 | 0.91 | KDM1A (0.36) | TRPV3KDM1AALOX5APFEN1GRIN1 | |
| SCHEMBL9631940 | 0.90 | SCN9A (0.34) | FFAR1ALOX5APFEN1 | |
| SCHEMBL9631421 | 0.90 | CYP2C9 (0.33) | FFAR1KDM1AIDO1 | |
| SCHEMBL9632437 | 0.89 | SCN9A (0.32) | ALOX5APFEN1 | |
| SCHEMBL9631110 | 0.88 | CNR1 (0.32) | — | |
| SCHEMBL9631946 | 0.88 | HPGD (0.32) | — | |
| SCHEMBL9405954 | 0.87 | GAA (0.32) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0364538-B1 | DIFLUOROBENZOL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |