Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 8/20 | 0.75 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796709 | 0.91 | FDPS (0.69) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL7614794 | 0.91 | FDPS (0.69) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL7620944 | 0.91 | FDPS (0.69) | FDPSMMP1MMP2MMP3MMP8 | |
| (Dipropylamino)Methylenediphosphonic Acid SCHEMBL12250787 | 0.86 | FDPS (1.00) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL7079157 | 0.79 | FDPS (0.77) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL15187674 | 0.77 | FDPS (0.56) | FDPS | |
| (Diethylamino)Methylenediphosphonic Acid SCHEMBL9630354 | 0.75 | FDPS (1.00) | FDPSMMP1MMP2MMP3MMP8 | |
| SCHEMBL11765105 | 0.74 | GGPS1 (0.55) | FDPSGGPS1LPAR3LPAR2S1PR2 | |
| SCHEMBL11080232 | 0.74 | GGPS1 (0.55) | FDPSGGPS1LPAR3LPAR2S1PR2 | |
| SCHEMBL1421092 | 0.74 | GGPS1 (0.55) | FDPSGGPS1LPAR3LPAR2S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335296-B1 | TC-99-M-W-ALKYLPHOSPHINIC-1-HYDROXYALKAN-1,1-DIPHOSPHONAT CONTAINING PREPARATIONS FOR BONES-SCINTIGRAPHY AND PREPARATION THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-15 | — | — | EP | disclosed |
| US-4910012-A | Technetium complexed with diphosphonate salt | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-20 | — | — | US | disclosed |
| EP-0335296-A2 | Tc-99-m-w-alkylphosphinic-1-hydroxyalkan-1,1-diphosphonat containing preparations for bones-scintigraphy and preparation thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-04 | — | — | EP | disclosed |
| US-3957160-A | Process for the prevention of precipitations in water or aqueous solutions | HENKEL & CIE G.M.B.H. (DT) | 1976-05-18 | — | — | US | disclosed |