SCHEMBL9630554

SCHEMBL9630554

CCCc1ccc(-c2ccc(C(C)C3CCC(CCC)CC3)c(F)c2F)cc1

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
FFAR4 Q5NUL3 6/20 0.32
MPL P40238 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9631468 0.93 RARB (0.32) MAOAMAOBFFAR4MPL
SCHEMBL9631641 0.92 RARB (0.38) MPL
SCHEMBL9630243 0.92 RARB (0.33) MAOAMAOBFFAR4MPL
SCHEMBL9630253 0.92 CHRM2 (0.31)
SCHEMBL9631596 0.92 MPL (0.32) FFAR4MPL
SCHEMBL9632665 0.91 RARB (0.35) MAOAMAOBFFAR4MPL
SCHEMBL9631142 0.91 RARB (0.39)
SCHEMBL9631304 0.88 RARB (0.38) MPL
SCHEMBL9630433 0.88 RARB (0.38) MPL
SCHEMBL9632544 0.87 RARB (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0364538-B1 DIFLUOROBENZOL DERIVATIVES MERCK PATENT GmbH (DE) 1992-05-06 EP disclosed