Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686496 | 0.93 | PPARA (0.64) | PPARANOTUMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7505230 | 0.93 | PPARA (0.64) | PPARANOTUMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6896391 | 0.89 | PPARA (0.46) | PPARANOTUMRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL25603631 | 0.87 | PPARA (0.57) | PPARAMAPK14NOS2RAB9ANPC1 | |
| SCHEMBL13991122 | 0.85 | PPARA (0.54) | PPARAMAPK14NOS2RAB9ANPC1 | |
| SCHEMBL11371889 | 0.81 | PPARA (0.51) | PPARAMAPK14NOS2RAB9ANPC1 | |
| SCHEMBL25653948 | 0.81 | PPARA (0.51) | PPARANOTUMMAPK14NOS2RAB9A | |
| SCHEMBL369102 | 0.81 | PPARA (0.71) | PPARARAB9ANPC1SMN1; SMN2S1PR1 | |
| SCHEMBL9629469 | 0.80 | — | — | |
| SCHEMBL1221911 | 0.80 | PPARA (0.61) | PPARANOTUMRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316783-B1 | PROCESS FOR THE PREPARATION OF HETERO-AROMATIC KETONES AND ALDEHYDES | BASF Aktiengesellschaft (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0316783-A1 | Process for the preparation of hetero-aromatic ketones and aldehydes | BASF Aktiengesellschaft (DE) | 1989-05-24 | — | — | EP | disclosed |