Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12450498 | 0.88 | PPARA (0.45) | PPARANOS2TP53NPC1RAB9A | |
| SCHEMBL11371889 | 0.85 | PPARA (0.51) | PPARANOS2MAPK14KCNH2ESR1 | |
| SCHEMBL9630698 | 0.85 | PPARA (0.55) | PPARANOS2MAPK14ESR1ESR2 | |
| SCHEMBL25653948 | 0.85 | PPARA (0.51) | PPARANOS2MAPK14KCNH2ESR1 | |
| SCHEMBL369102 | 0.84 | PPARA (0.71) | PPARAKCNH2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13991120 | 0.84 | PPARA (0.54) | PPARANOS2EPHX2NPC1RAB9A | |
| SCHEMBL25603631 | 0.83 | PPARA (0.57) | PPARANOS2MAPK14NPC1RAB9A | |
| SCHEMBL18256139 | 0.83 | PPARA (0.43) | PPARANPC1RAB9ASMN1; SMN2S1PR1 | |
| SCHEMBL1233522 | 0.81 | PPARA (0.55) | PPARANOS2MAPK14ESR1ESR2 | |
| SCHEMBL9285410 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080312292-A1 | Antipruritics | YASUI KIYOSHI | 2008-12-18 | — | — | US | disclosed |
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | SHIONOGI & CO., LTD. (JP) | 2007-02-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070027144-A1 | Novel use of cannabinoid receptor agonist | CNR2, CNR1, OPRM1 | PPARA 310/4885NOS2 785/4885MAPK14 2594/4885 |
| US-20080312292-A1 | Antipruritics | CNR1, CNR2, OPRL1 | PPARA 321/4885NOS2 1133/4885MAPK14 1046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.