Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 9/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9631939 | 0.88 | MEN1 (0.32) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL9633200 | 0.86 | MEN1 (0.31) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL9633203 | 0.86 | MEN1 (0.31) | MEN1MAPTKMT2ATDP1 | |
| SCHEMBL9632228 | 0.85 | MEN1 (0.47) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL9633208 | 0.83 | MEN1 (0.44) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL9189608 | 0.76 | PPARG (0.43) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL9630803 | 0.75 | MEN1 (0.52) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL7837647 | 0.75 | MEN1 (0.46) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL7837649 | 0.73 | MEN1 (0.45) | MEN1MAPTKMT2ATDP1PPARG | |
| SCHEMBL9631385 | 0.73 | MEN1 (0.34) | MEN1MAPTKMT2ATDP1PSEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5104888-A | Anticholesterol or antidiabetic agents | SANKYO COMPANY, LIMITED (JP) | 1992-04-14 | — | — | US | disclosed |
| EP-0207581-B1 | THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE | SANKYO COMPANY LIMITED (JP) | 1990-09-12 | — | — | EP | disclosed |
| EP-0207581-A2 | Thiazolidine derivatives, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-01-07 | — | — | EP | disclosed |