Sugi Predict

Sugi Predict / Compounds / SCHEMBL9633203

SCHEMBL9633203

SCHEMBL9633203

Cc1c(C)c2c(c(C)c1OCC(=O)OC(C)(C)C)C(=NO)CC(C)(COc1ccc(CC3(CC(=O)OC(C)(C)C)SC(=O)N(CC(=O)OC(C)(C)C)C3=O)cc1)O2

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9633200 1.00 MEN1 (0.31) MEN1MAPTKMT2ATDP1
SCHEMBL9631939 0.92 MEN1 (0.32) MEN1MAPTKMT2ATDP1
SCHEMBL9630751 0.86 MEN1 (0.44) MEN1MAPTKMT2ATDP1
SCHEMBL9630825 0.86 MEN1 (0.33) MEN1MAPTKMT2ATDP1
SCHEMBL9630830 0.86 MEN1 (0.33) MEN1MAPTKMT2ATDP1
SCHEMBL9630795 0.84 PPARG (0.41) MEN1MAPTKMT2ATDP1
SCHEMBL9630790 0.84 PPARG (0.41) MEN1MAPTKMT2ATDP1
SCHEMBL9631385 0.78 MEN1 (0.34) MEN1MAPTKMT2ATDP1
SCHEMBL9631020 0.76 PPARG (0.43) MEN1MAPTKMT2ATDP1
SCHEMBL9631382 0.76 PPARG (0.42) MEN1MAPTKMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5104888-A Anticholesterol or antidiabetic agents SANKYO COMPANY, LIMITED (JP) 1992-04-14 — — US disclosed
EP-0207581-B1 THIAZOLIDINE DERIVATIVES, THEIR PREPARATION AND USE SANKYO COMPANY LIMITED (JP) 1990-09-12 — — EP disclosed
EP-0207581-A2 Thiazolidine derivatives, their preparation and use SANKYO COMPANY LIMITED (JP) 1987-01-07 — — EP disclosed