Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.52 |
| ▸ | HINT1 | P49773 | 3/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 7/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PNP | P00491 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630796 | 1.00 | BCHE (0.55) | BCHEABCB1HINT1HPRT1ADORA3 | |
| SCHEMBL9704169 | 0.88 | BCHE (0.58) | BCHEABCB1HINT1HPRT1ADORA3 | |
| SCHEMBL15046016 | 0.88 | BCHE (0.58) | BCHEABCB1HINT1HPRT1ADORA3 | |
| SCHEMBL21340996 | 0.87 | BCHE (0.51) | BCHEABCB1HINT1HPRT1PNP | |
| SCHEMBL9704154 | 0.86 | BCHE (0.57) | BCHEABCB1HPRT1ADORA3PNP | |
| SCHEMBL9752192 | 0.85 | MEN1 (0.54) | BCHEABCB1 | |
| SCHEMBL9752191 | 0.85 | MEN1 (0.54) | BCHEABCB1 | |
| SCHEMBL15257632 | 0.85 | BCHE (0.58) | BCHEABCB1HINT1HPRT1ADORA3 | |
| Carbovir SCHEMBL9867194 | 0.84 | NR1I2 (0.56) | BCHEHPRT1ADORA3PNP | |
| Carbovir SCHEMBL3778804 | 0.84 | NR1I2 (0.56) | BCHEHPRT1ADORA3PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089500-A | Viricides; hepatitis, aids | BURROUGHS WELLCOME CO. (US) | 1992-02-18 | — | — | US | disclosed |
| US-5034394-A | Therapeutic nucleosides | BURROUGHS WELLCOME CO. (US) | 1991-07-23 | — | — | US | disclosed |